产品货号：
Z17693
中文名称：
GLUR1/GRIA1抗体
英文名称：
Anti-GLUR1/GRIA1 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-GLUR1/GRIA1 Antibody |
| 指标别名 | glutamate ionotropic receptor AMPA type subunit 1;GLUH1;GLUR1;GLURA;GluA1;HBGR1;GRIA1 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB |
| 基因名称 | GRIA1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence at the C-terminus of human GRIA1(881-895aa HDFPKSMQSIPCMSH),different from the related rat and mouse sequences by one amino acid. |
| 实际分子量 | 101KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | GLUR1,Glutamate receptor 1,is a protein that in humans is encoded by the GLUR1 gene.The sequence of GLUR1 was predicted to encode a 907-amino acid protein that had 97% identity to one of the rodent kainate receptor subunits.GLUR1 mRNA is widely expressed in human brain.Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes.These receptors are heteromeric protein complexes with multiple subunits,each possessing transmembrane regions,and all arranged to form a ligand-gated ion channel.The classification of glutamate receptors is based on their activation by different pharmacologic agonists.The GRIA1 belongs to a family of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate(AMPA) receptors.Each of the members(GRIA1-4) include flip and flop isoforms generated by alternative RNA splicing.The receptor subunits encoded by each isoform vary in their signal transduction properties.The isoform presented here is the flop isoform.In situ hybridization experiments showed that human GRIA1 mRNA is present in granule and pyramidal cells in the hippocampal formation. |
| Uniprot ID | P42261 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | glutamate receptor,ionotropic,AMPA 1 |
| 蛋白名全称 | Glutamate receptor 1(GluR-1) |
| 推荐稀释比 | Western blot(WB) 1:500～2000 |
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